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Immunologic priming with recombinant hepatitis A virus capsid proteins produced in Escherichia coli

  • Powdrill T
  • Johnston J
Journal of Virology (1991) 65(5) 2686-2690
DOI: 10.1128/jvi.65.5.2686-2690.1991
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Abstract

Hepatitis A virus capsid proteins (VP0, VP3, and VP1) have been synthesized in Escherichia coli for use in antigenic and immunogenic analyses. Rabbits immunized with each of these individual recombinant capsid proteins developed a rapid neutralizing antibody response when subsequently challenged with a subimmunogenic dose of whole virus.

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Powdrill, T. F., & Johnston, J. M. (1991). Immunologic priming with recombinant hepatitis A virus capsid proteins produced in Escherichia coli. Journal of Virology, 65(5), 2686–2690. https://doi.org/10.1128/jvi.65.5.2686-2690.1991

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