Exercise Improves the Function of Endothelial Cells by MicroRNA

Abstract

Vascular diseases induced by diabetes and obesity (e.g., atherosclerosis) are associated with insulin resistance (IR), which leads to endothelial cell dysfunction due to metabolic disorder and oxidative stress. Research conducted by Cai showed that exercise prevented the formation of aortic plaque by regulating miR-429 and its target resistin, thus might be a novel potential therapeutic strategy for cardiovascular diseases.