Abstract
An entirely biodegradable nano-photosensitizer platform (PPE-FP2) was fabricated by conjugating the photosensitizer TFPC to hydrophilic polyphosphoesters (PPEs) for efficiently liberating photosensitizers at the tumor site. The complete biodegradability of PPE-FP2 avoided residual nanoparticles in vivo after therapy, realizing reliable and effective photodynamic therapy.
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CITATION STYLE
Liu, Z., Wu, M., Xue, Y., Chen, C., Wurm, F. R., Lan, M., & Zhang, W. (2020). Hydrophilic polyphosphoester-conjugated fluorinated chlorin as an entirely biodegradable nano-photosensitizer for reliable and efficient photodynamic therapy. Chemical Communications, 56(16), 2415–2418. https://doi.org/10.1039/d0cc00142b
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