Scanning electron microscope study of herpes simplex virus experimental disciform keratitis

Abstract

Scanning electron microscopy of the endothelium of experimental disciform kertis revealed corneal endothelial changes which distinguished disciform oedema from the re progressive stages of disciform keratitis. The endothelium of corneas with disciform oedema tre wholly intact and characterised by subtle morphological alterations. In contrast, the more progre sse stages of disciform keratitis were characterised by massive destruction and denudation of the endothelium. The significance of these observations is discussed.