Novel forms of lipodystrophy: Why should we care?

Abstract

Greater awareness and correct diagnosis of previously described and novel forms of lipodystrophy may spare patients an arduous voyage through misdiagnoses and unnecessary treatments. Certain lipodystrophy-associated genotypesmay in fact be more common in milder clinical conditions, such as metabolic syndrome. A worldwide registry of patients with lipodystrophy and lipodystrophy-related genetic mutations would certainly benefit our concerted efforts in learning about the natural history, developing better diagnostic criteria, and providing safe and effective treatment. © 2013 by the American Diabetes Association.