Alkalophilic Protease Producing Bacteria and Some Biotechnological Potentials

Abstract

Background: Extremophiles are a hot topic in the field of biotechnology for their immense potential and applications in multiple industries. Objectives: The present review aims to sum up the potential applications of alkalophilic protease-producing bacteria and their optimized growth requirement. The isolation, characterization, and optimization of various isolates (especially of genus Bacillus) from different harsh niches, including soil samples from deserts and soil having decaying matters, wastewaters from industries, soda lakes, and alkaline springs have been reported in this review. Methodology: All the relevant papers published from 2013-2020 were looked over numerous sources like Google Scholar, Medline, PubMed, Research Gate, Science Direct, Scopus and Web of Science. Results: Most of the microbial life found in extreme alkaline habitats are found to form a variety of enzymes and an array of other substances of biotechnological interests. These enzymes, especially proteases, are exploited in industries globally because of their ability to withstand rigorous industrial reactions and conditions. Conclusion: Though a number of alkalophilic protease-producing bacteria have been isolated, still a large number of these micro-organisms are unidentified. The current demand for biotechnological products from them appeals to the need for isolation of unidentified bacteria.