Flavonoids from the leaves and stems of Rhodiola ishidae (Crassulaceae)

Abstract

Twenty-six flavonoids including flavonols, C-glycosylflavones, flavanone and anthocyanin were isolated from the leaves and stems of Rhodiola ishidae. Major flavonoids were flavonol glycosides based on herbacetin, gossypetin, kaempferol and quercetin, and identified by UV spectral survey, HR-MS, LC-MS, acid hydrolysis, NMR and/or HPLC and TLC comparisons with authentic samples. Of these flavonoids, three compounds, herbacetin 7-O-glucuronopyranoside-8-O-glucopyranoside, gossypetin 3-O-(2''-malonylxylopyranoside)-8-O-glucopyranoside and naringenin 7-O-sophoroside, were reported in nature for the first time. Flavonoid characters of R. ishidae were chemotaxonomically discussed.