To study umbilical cord blood TSH values in newborn in BHMRC over a period of 1 year

Abstract

Objectives: To study the association between umbilical cord blood TSH values and innate factors namely sex, birth, weight, gestational age. To study the effect of birth asphyxia on cord blood TSH. To estimate incidence of congenital hypothyroidism in newborns.Methods: This study was carried out at Batra Hospital and Medical Research Centre, New Delhi from July 2008 to June 2009. Cord blood was collected immediately after birth and sent for TSH assay.Result: In our study, we found no significant difference in cord blood TSH according to mode of delivery, pre-eclampsia, birth weight, male and female newborns. We found a significantly high mean cord blood TSH in newborn with APGAR < 7. One newborn was found to have congenital hypothyroidism.Conclusion: This study helps to find out normative and mean values of cord blood TSH and to evaluate the effect of various perinatal factors on umbilical cord blood TSH.