Heterocycles based on the chemistry of alkylidenecyclopropanes and (aza)-cyclopropenes

Abstract

Alkylidenecyclopropyl, cyclopropenyl, or azacyclocyclopropenyl ketones or carboxylates have been demonstrated to be versatile starting materials for the synthesis of oxygen- and/or nitrogen-containing heterocycles. The reactivities and regioselectivities may be nicely controlled by subtle choice of the catalysts and reaction condition parameters. © 2008 IUPAC.