Unusual reactivity of aliphatic and aromatic amines with bromoalkyl derivatives of thiacalix[4]arene in 1,3-alternate stereoisomeric form

Abstract

For the first time a series of new cationic amphiphilic p-tert-butylthiacalix[4]arene derivatives adopting 1,3-alternate stereoisomeric form was synthesized by quaternization of several tertiary amines and N-heterocycles. The structure of all products was well-defined using modern physical technics. The influence of calixarene and amine sterical hindrances on reactivity is discussed.