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An epigenetic barrier sets the timing of human neuronal maturation

Nature (2024) 626(8000) 881-890
DOI: 10.1038/s41586-023-06984-8
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Abstract

The slow maturation of human neurons is regulated by epigenetic modification in nascent neurons, mediated by EZH2, EHMT1, EHMT2 and DOT1L.

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Ciceri, G., Baggiolini, A., Cho, H. S., Kshirsagar, M., Benito-Kwiecinski, S., Walsh, R. M., … Studer, L. (2024). An epigenetic barrier sets the timing of human neuronal maturation. Nature, 626(8000), 881–890. https://doi.org/10.1038/s41586-023-06984-8

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