Radical Scavenging Activity and Antibacterial Effect of Three Cyclamen L. Tuber Extracts on Some Fish Pathogens

Abstract

Cyclamen L. is a member of Primulaceae family, a geophyte, which have been utilized for their biological activities in folk medicine. The aim of this study is to investigate the antibacterial activity of three Cyclamen species on some fish pathogens as well as their radical scavenging activity potentials. C. cilicium Boiss. & Heldr., C. pseudibericum Hildebr. and C. hederifolium Aiton were collected from different regions in Turkey. Cyclamen tubers were extracted in ethanol and then DPPH, ABTS and NO methods were utilized for the assurance of radical scavenging activities of the extracts. Antibacterial activity of the extracts were determined in vitro against five bacterial fish pathogens, namely, Vagococcus salmoninarum, Staphylococcus epidermidis, Lactococcus garvieae, Vibrio anguillarum and Yersinia ruckeri. All the tested tuber extracts exhibited moderate antibacterial activity against four bacteria and the radical scavenging activity in the order of potency: C. cilicium>C. pseudibericum>C. hederifolium. In conclusion, this study showed that the Cyclamen species have moderate antibacterial activity against fish pathogenic bacteria except V. anguillarum. (English) [ABSTRACT FROM AUTHOR]