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A new concept in double duplex DNA invasion by chiral PNAs which simultaneously depress PNA-PNA and improve PNA-DNA duplex stability.

Nucleic acids symposium series (2004) (2007) (51) 19-20
DOI: 10.1093/nass/nrm010
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Abstract

By using suitably designed chiral, lysine-based PNAs (chPNAs), the stability of complementary chPNAchPNA duplexes can be depressed, maintaining or improving at the same time the stability of the corresponding PNA-DNA duplexes. This approach could be used in order to develop chPNAs able to perform double duplex DNA invasion.

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APA

Sforza, S., Tedeschi, T., Corradini, R., & Marchelli, R. (2007). A new concept in double duplex DNA invasion by chiral PNAs which simultaneously depress PNA-PNA and improve PNA-DNA duplex stability. Nucleic Acids Symposium Series (2004), (51), 19–20. https://doi.org/10.1093/nass/nrm010

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