Collagen-The Biomaterial

Abstract

Collagen-The biomaterials for their enhanced biocompatibility and improved controllable biodegradability has immense and vital role in biomedical field for Drug and gene carrier, tissue engineering and wound dressing [1-4]. Collagen acts as a structural scaffold in tissues. Collagen scaffolds have also shown to accurately deliver cells, proteins, drugs and nucleic acids on a predictable and long-term basis Sano A et al. [5]. Finally, a recent clinical trial using adenovirus in collagen gel has cleared the path for future clinical studies on gene therapy delivered by collagen matrix Muller WE [6]. Because of collagen’s biodegradability and low immunogenicity nature, collagen is used as substrate for topical and internal pharmaceutical application.