Reducing Inflammation: Statins or Lifestyle?

Abstract

An elevated C-reactive protein level is an inflammatory marker associated with an increased risk in cardiovascular disease. Regular long-term exercise, a cholesterol-lowering diet (a diet low in saturated fat and high in viscous fiber and plant sterols), and statin pharmacotherapy have all been shown to reduce C-reactive protein levels. The purpose of this article is to describe the research available regarding lowering of C-reactive protein levels and reducing incidence of cardiovascular disease. Specifically, the article will compare the use of statin therapy, regular physical activity, and a cholesterol-lowering diet. The effectiveness of each intervention will be evaluated along with the risks and benefits associated with treatment. © 2012, SAGE Publications. All rights reserved.