Successful Treatment of Canine Parvovirus Infection in Naturally Infected Puppies

Abstract

Background and Objective: Canine Parvovirus infection (CPV) causes high moralities among infected puppies, low survival and recovery rate in most of treated cases.So, the aim of this study was to develop a successful method for treatment of CPV infection in dogs with high recovery rate and to evaluate different types of treatment used to treat CPV infection.Materials and Methods: In this study, 360 puppies showing signs suggestive for CPV infection were subjected to clinical examination; Rapid Immunochromatography assay (IC) on fecal samples to detect viral antigen.Treatment of disease was applied using supportive classical treatment for all of the infected puppies while 2 groups (each of 120 puppies) received also Feliserin Plus and Zylexis as trail for treatment using antibodies specific against Feline panleukopenia virus (FPV) as a source for interferon to control viral infection.Results: Clinical examination of diseased puppies revealed the presence of depression, pyrexia, anorexia, thirst, vomiting, diarrhea and dehydration.The IC on fecal samples was positive for CPV in all the 360 examined puppies.Recovery rate in the form of clinical improvement and survival of diseased animals were significantly higher in the group treated by Feliserin Plus (81.7%), followed by the group treated by Zylexis (16.6%).Conclusion: The results of this study exhibited that the use of Feline specific neutralizing antibodies against FPV showed promising results against CPV infection in comparison to the old classical treatment and could be applied for CPV infection in diseased dogs.