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Viral Load Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospitalized Individuals with Coronavirus Disease 2019

Open Forum Infectious Diseases (2021) 8(8)
DOI: 10.1093/ofid/ofab153
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Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) kinetics remain understudied, including the impact of remdesivir. In hospitalized individuals, peak sputum viral load occurred in week 2 of symptoms, whereas viremia peaked within 1 week of symptom-onset, suggesting early systemic seeding of SARS-CoV-2. Remdesivir treatment was associated with faster viral decay.

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Regan, J., Flynn, J. P., Rosenthal, A., Jordan, H., Li, Y., Chishti, R., … Li, J. Z. (2021). Viral Load Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospitalized Individuals with Coronavirus Disease 2019. Open Forum Infectious Diseases, 8(8). https://doi.org/10.1093/ofid/ofab153

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