Immune responses and HIV: A little order from the chaos

Abstract

HIV is evolution gone mad and bad. The virus infects a person and rapidly diversifies to become a huge swarm of viruses, each equipped differently to resist the onslaught of diverse T cells and antibodies. We can't expect to predict details of the struggle between virus and immunity, right? Wrong - maybe we can make some predictions, say two new landmark studies with potentially huge consequences for AIDS vaccine design. JEM © The Rockefeller University Press.