A review of cellular reprogramming: Limitations and recent advances

Abstract

Cellular reprogramming has been around for many years offering opportunities in areas such as regenerative medicine. New technologies and methods have merged since its origin. However, no method has yet been totally successful. A wide range of possible applications, from healing small wounds to curing complex illnesses like Alzheimer, is the reason to continue the exhaustive research in this area. In this review paper, we make a compilation of the most relevant reprogramming technologies. We go over the initial techniques to the most recent advances, especially highlighting each of their benefits and limits. Finally, we make a comparison of the current reprogramming technologies in regenerative medicine and remark the importance of continuing the present investigations.