Chronic hand eczema is a common and often debilitating condition. Alitretinoin, a 9-cis-retinoic acid and pan-retinoic acid agonist, is a new and effective systemic treatment for chronic hand eczema, which provides another treatment option. A "clear" or "almost clear" response can be achieved in up to half of patients within a 24-week course of treatment. Even higher rates of remission can be obtained with a longer duration of treatment. Alitretinoin has a favorable overall profile of adverse effects; however, female patients who are at risk of becoming pregnant should follow a strict pregnancy-prevention program due to the teratogenic effects of this drug.
CITATION STYLE
King, T., McKenna, J., & Alexandroff, A. B. (2014). Alitretinoin for the treatment of severe chronic hand eczema. Patient Preference and Adherence, 8, 1629–1634. https://doi.org/10.2147/PPA.S38830
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