Assessment of the developmental defects of the enamel in children and adolescents with sickle cell disease: A comparative study

Abstract

Background: Sickle cell disease (SCD) is the most important hemoglobinopathy in terms of frequency and social impact and can affect the stomatognathic system. Aim: To assess and compare the developmental defects of the enamel (DDE) in children and adolescents with and without SCD. Design: This was a cross-sectional, analytical, and comparative study of 210 children and adolescents aged 5–18 years, who visited the Hematology and Hemotherapy Hospital of Pernambuco. Results: Developmental defects of the enamel were observed in 55.2% of the SCD patients and 35.2% of the non-SCD patients (healthy group; p