Chemical constituents and cytotoxicity of Lepidotrigona ventralis propolis

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Abstract

From propolis of Lepidotrigona ventralis stingless bee collected in Tuyen Quang province, eight compounds were isolated and determined as lantanolic acid (1), moronic acid (2), (+)-eudesmin (3), (+)-yangambin (4), (+)-syringaresinol (5), (+)-pinoresinol (6), dihydroconiferyl alcohol (7) and vanillin (8) using NMR and MS spectral data. Compounds 1 and 2 showed significant cytotoxicity against HepG-2 cancer cell line with IC50 values of 25.84±0.48 and 39.92±1.14 μg/mL, respectively.

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Thanh, L. N., Thu, N. A., Oanh, V. T. K., Hue, V. T., Minh, N. T., Minh, N. P. N., … Lien, N. T. P. (2023). Chemical constituents and cytotoxicity of Lepidotrigona ventralis propolis. Vietnam Journal of Chemistry, 61(1), 74–79. https://doi.org/10.1002/vjch.202200031

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