Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting

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Abstract

In this contribution, a channel aspect ratio of >2 was used to access high velocity regimes to provide confined sample cores by Dean focussing in advance of linear inertial focussing. This produces a singular separation origin with a mirrored transport path for efficient particle and blood cell sorting, while also increasing the spatial resolution for multiscale sorting.

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Holloway, P. M., Butement, J., Hegde, M., & West, J. (2018). Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting. Biomicrofluidics, 12(4). https://doi.org/10.1063/1.5038965

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