Bimetallic nanoparticles from coinage metals (Cu, Ag, Au) and its biomedical applications: A Review

Abstract

Efficacy and synthesis of nanoparticles has been rapidly increased from last decades, with the greater acceptability of green synthesis route over chemical methods; for being less toxic, environment friendly nature and sustainability. Effective antimicrobial agent and anti-cancer agents are in need worldwide because of increased mortality due to microbial epidemic and cancer. Recently, bimetallic nanoparticles prepared from coinage metals (Cu, Ag, Au) has appeared to be more favoured due to their straightforward preparation techniques, allowing control over size and shape. Bimetallic nanoparticles are of particular interest, as they exhibit unique mixing patterns and synergistic effects when two metal nanoparticles combine opening up new possibilities in therapeutic applications viz., anti-diabetic, anti-cancer, anti-inflammatory, antioxidant, and antimicrobial properties. This review paper primarily focuses on the exploration of diverse green-synthesized bimetallic nanoparticles involving coinage metals (Ag, Au, Cu) and their applications in the antimicrobial and anti-cancer activities.