Three common preparation methods of hydroxyapatite

Abstract

Hydroxyapatite has good stability, biological activity and biocompatibility, the calcium ions can be a variety of metal ions by ion exchange reaction, form M apatite of the corresponding metal ions (M on behalf of metal ions that replace calcium). Hydroxyapatite also has a good ability of bone conduction, bio decomposition and bone formation induction, make it an excellent and nearly ideal repair and replacement material for human teeth and bones when damaged. However, due to its low strength, poor toughness, difficult to form, poor corrosion resistance, hydroxyapatite has not been widely used. Therefore, the preparation of hydroxyapatite with superior comprehensive properties and more ideal composite materials has become the focus of research in recent years. This article is written based on the research status of hydroxyapatite, summarizing the origin, development, preparation, application and development prospect of hydroxyapatite. Emphatically analyzing the advantages and disadvantages of three common methods, including hydrothermal method, solvothermal method and homogeneous precipitation method, the structure, size, properties and application of hydroxyapatite obtained using these methods are also discussed. Views on the future development prospect and research direction of hydroxyapatite are also put forward.