Determination of Protonation Constants and Stability Constants of Lanthanides with Derivative of H4DOTA Complexes by the UV-VIS Spectrophotometry and Potentiometry

Abstract

Methods of static potentiometry and UV-VIS spectrophotometry were applied for the determination of protona- tion constants of 2 = 21.4) and [H3A] (log by the static potentiometry. The stability constants of Ho-DOTA(NH2) (log KHo DOTA(NH2) = 18.0) and Y-DOTA(NH2) (log KY-DOTA(NH2) = 17.8) complexes were determined by UV-VIS spectrophotometry using the competitive reaction of the DOTA(NH2) – metal complexes with Arsenazo III.