Association of immune response to endothelial cell growth factor with early disseminated and late manifestations of lyme disease but not posttreatment lyme disease syndrome

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Abstract

Endothelial cell growth factor has been recently proposed as a potential autoantigen in manifestations of Lyme disease that are thought to involve immune-mediated mechanisms. Our findings indicate that a humoral immune response to this protein is not associated with posttreatment Lyme disease syndrome.

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Tang, K. S., Klempner, M. S., Wormser, G. P., Marques, A. R., & Alaedini, A. (2015). Association of immune response to endothelial cell growth factor with early disseminated and late manifestations of lyme disease but not posttreatment lyme disease syndrome. Clinical Infectious Diseases, 61(11), 1703–1706. https://doi.org/10.1093/cid/civ638

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