Background and objective: The reported incidence of persistent hypoparathyroidism varies widely, and consensus on a definition is lacking. The objective was to evaluate the real-life incidence of persistent hypoparathyroidism by investigating a new pragmatic definition. Methods: This retrospective multicenter cohort study evaluated the effect of different definitions for persistent hypoparathyroidism on the incidence of hypoparathyroidism. In addition, risk factors for hypoparathyroidism were analyzed. Results: In total, 749 patients were included. Using the new pragmatic definition, we report an incidence of 7.9% of persistent hypoparathyroidism. When applying other commonly used definitions, incidence varied between 11.8% and 22.1%. Risk factors were parathyroid autotransplantation, presence of another surgical complication, and low postoperative serum calcium. Conclusions: Our data show that the incidence of persistent hypoparathyroidism in the literature may vary through the use of different definitions. This study indicates that a new pragmatic definition of persistent hypoparathyroidism has the potential to enable unbiased comparison between studies.
CITATION STYLE
Lončar, I., van Kinschot, C. M. J., van Dijk, S. P. J., Franssen, G. J. H., Visser, E. E., Peeters, R. P., … van Ginhoven, T. M. (2022). Persistent post-thyroidectomy hypoparathyroidism: A multicenter retrospective cohort study. Scandinavian Journal of Surgery, 111(2). https://doi.org/10.1177/14574969221107282
Mendeley helps you to discover research relevant for your work.