Synthesis and characterization of some heterocyclic compounds derived from 2-mercapto benzothiazole

Abstract

treatment of 2-mercapto benzothiazole with hydrazine hydrate to obtain the intermediate of 2-hydrazinobenzothiazole (S1). A series of (S1-S13) compound has been prepared after treatment compound (S1) with phthalic anhydride two derivatives of pyridazinone and phthalazinone has been obtained (S3). The reaction (S1) with phenylisothiocyanate and ethyl chloroacetate afforded 3-phenyl-1, 3-thiazolidin-2,4-dione-2-(benzothiazole-2yl-hydrazone) (S13). The reaction of (S1) with aromatic aldehyde synthesized azomethines (S6-S8) then treated with mercaptoacetic acid to obtained (S9-S11). The reaction of (S1) with p-bromophenacyl bromide afforded another 1, 2, 4-triazole (S2). The reaction between (S1) and chloroacetic acid gave (S4). The compound (S4) been reacted with ortho- A minoaniline result the benzimidazole (S5). Using M.P and FT-IR to test all compounds and using H1-NMR & C13-NMR spectra for some of them.