Self-renewal equality in pancreas homeostasis, regeneration, and cancer

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Abstract

Two studies by Lodestijn et al. in Cell Stem Cell and Cell Reports reveal a lack of stem cell hierarchies in acinar cell-derived tissue renewal and host instructed clonogenic growth of pancreatic cancer, thereby elucidating determinants of pancreas regeneration and cancer.

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Falcomatà, C., & Saur, D. (2021). Self-renewal equality in pancreas homeostasis, regeneration, and cancer. Cell Reports, 37(11). https://doi.org/10.1016/j.celrep.2021.110135

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