Examining the cognitive effects of a special extract of Bacopa monniera (CDRI 08: KeenMind): A review of ten years of research at Swinburne University

Abstract

Bacopa monnieri (EBm), an Indian aquatic herb, has been used in traditional Ayurvedic medicine for centuries for indications related to memory and inflammation. More recently specific extracts of EBm have emerged that have been subjected to rigorous in vitro, animal and now human clinical trials. In this paper we discuss some of these studies with special reference to mechanisms and efficacy of a special extract of Bacopa (CDRI 08). Studies using this extract indicate that CDRI 08 has several modes of action on the human brain. Promising indications for use in humans include improving cognition in the elderly and in patients with neurodegenerative disorders.