Abstract
In patients with sudden severe headache and a negative computed tomography (CT) scan, a lumbar puncture (LP) is performed to rule in or out a subarachnoid haemorrhage (SAH), but this procedure is under debate. In a hospital-based series of 30 patients with sudden headache, a negative CT scan but a positive LP (defined as detection of bilirubin >0.05 at wavelength 458 nm), we studied the chance of harbouring an aneurysm and the clinical outcome. Aneurysms were found in none of both patients who presented within 3 days, in 8 of the 18 (44%) who presented within 4-7 days and in 5 of the 10 (50%) who presented within 8-14 days. Of the 13 patients with an aneurysm, 3 (23%) had poor outcome. In patients who present late after sudden headache, the yield in terms of aneurysms is high in those who have a positive lumbar puncture. In patients with an aneurysm as cause of the positive lumbar puncture, outcome is in the same range as in SAH patients admitted in good clinical condition. © Springer-Verlag 2011.
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Horstman, P., Linn, F. H. H., Voorbij, H. A. M., & Rinkel, G. J. E. (2012). Chance of aneurysm in patients suspected of SAH who have a “negative” CT scan but a “positive” lumbar puncture. Journal of Neurology, 259(4), 649–652. https://doi.org/10.1007/s00415-011-6228-1
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