Epigenetics in Periodontal Diseases

Abstract

Genetics and epigenetics is the process by which genes were expressed or suppressed through polymorphism, demethylation, and deacetylation. Many Environmental factors such as race, gender, diabetes, education, smoking etc. can have profound effects on the epigenetic changes and induce susceptibility to disease. Periodontal diseases are bacterial infections in which predominantly gram negative anaerobic bacteria colonize the sub gingival areas and triggers an inflammatory response that affect the periodontium; periodontitis is a periodontal disease that destroys the tissue and bone surrounding the tooth. Periodontitis is responsible for tooth loss in adults.