Performance of the BioPlex 2200 multiplexing immunoassay platform for the detection of herpes simplex virus type 2 specific antibodies in African settings

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Abstract

The BioPlex platform was evaluated for the detection of herpes simplex virus 2 (HSV-2) antibodies in sub-Saharan Africa individuals in comparison to clinicovirological standards and compared to HerpeSelect. The sensitivities and specificities were, respectively, 88.9% and 93.5% for BioPlex and 89.9% and 92.7% for HerpeSelect. The agreement between both assays was 95.7%. Copyright © 2011, American Society for Microbiology. All Rights Reserved.

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LeGoff, J., Grésenguet, G., Gody, C., Longo, J. D. D., Khonde, N., Weiss, H. A., … Malkin, J. E. (2011). Performance of the BioPlex 2200 multiplexing immunoassay platform for the detection of herpes simplex virus type 2 specific antibodies in African settings. Clinical and Vaccine Immunology, 18(7), 1191–1193. https://doi.org/10.1128/CVI.05003-11

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