Effects of inorganic or organic selenium on immunoglobulins in swine

Abstract

A study was conducted to determine if Se source fed during gestation and lactation affects passive transfer of immunoglobulins. Sixty days prior to breeding (d -60), gilts were randomly assigned to one of three treatments prior to breeding and throughout gestation: control (Control, no supplemental Se; n = 8), inorganic Se (Inorganic Se, 0.3 ppm; n = 4) and organic Se (Organic Se, 0.3 ppm; n = 4). Blood was collected on d -60, 57 and 113 of gestation and on d 21 of lactation and milk was collected at d 0, 1, 7, 14, and 21 of lactation. Blood was collected from piglets at d 0, 1, 7, 14, and 21 of age. Gilts fed organic Se had greater (P < 0.05) circulating concentrations of Se than Inorganic and Control gilts. Regardless of treatment, circulating concentrations of Se were greatest (P < 0.05) at d -60 compared to all other days. Serum concentrations of IgG were greatest (P < 0.05) in gilts at d 57 of gestation compared to d 113. Serum concentrations of IgA were greatest (P < 0.05) on d 113 of gestation and d 21 of lactation compared to d -60 and 57. Serum concentrations of IgM were greater (P < 0.05) at d 57 compared to d -60. Inorganic gilts had greater (P < 0.05) colostral and milk concentrations of IgG and IgM than Organic or Control gilts. Circulating concentrations of Se in piglets were greatest (P < 0.05) at d 14 and 21 of age compared to all other days. Piglets from gilts supplemented with organic Se had greater (P < 0.05) circulating concentrations of Se on d 1 versus piglets from gilts supplemented with no additional Se. The immunoglobulin concentrations of IgG, IgA, and IgM were lowest (P < 0.05) on d 0 and then increased when compared to d 1. The addition of different sources of Se did not affect the immunoglobulin concentrations in the gilt or piglet. © 2013 Gelderman and Clapper; licensee BioMed Central Ltd.