Postbooster antibodies from humans as source of diphtheria antitoxin

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Abstract

Diphtheria antitoxin for therapeutic use is in limited supply. A potential source might be affinity-purified antibodies originally derived from plasma of adults who received a booster dose of a vaccine containing diphtheria toxoid. These antibodies might be useful for treating even severe cases of diphtheria.

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Bermejo-Martin, J. F., Avila-Alonso, A., González-Rivera, M., Tamayo, E., Eiros, J. M., & Almansa, R. (2016). Postbooster antibodies from humans as source of diphtheria antitoxin. Emerging Infectious Diseases, 22(7), 1265–1267. https://doi.org/10.3201/eid2207.151670

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