The 5 Hallmarks of Biomaterials Success: An Emphasis on Orthopaedics

Abstract

Over the past 200 years, there has been significant advancements in thefields of bioengineering and orthopaedics. Investigators, clinicians and manufactures are learning that the success of implant systems is not limited to a single factor, but a combination of variables thatmust work in unison to provide stability and high survivorship. Innovationscontinue to advance these fields and include: biomimetic alterations,three-dimensional, patient-specific reconstructions and novel coatings tomitigate aseptic loosening or other pathologies. However, implant systemscontinue to fail in clinical practice since they do not adhere to keyfundamental principles. Therefore, this article is intended to highlight 5hallmarks of biomaterials that should be considered during design, surgery,and post-operative rehabilitation.