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New insights on the role of CD8+CD57+ T-cells in cancer

OncoImmunology (2012) 1(6) 954-956
DOI: 10.4161/onci.20307
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Abstract

Incomplete diferentiation of CD8+ cytotoxic t-lymphocytes (CtLs) in the tumor microenvironment is associated with cancer progression. we describe a new type of tumor-infltrating CD8+CD57+ t cell in cancer with hybrid phenotypic and functional properties of both an early efector-memory cell and a terminally-diferentiated efector cell. these cells behave as incompletely-diferentiated CtLs. © 2012 Landes Bioscience.

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Wu, R. C., Hwu, P., & Radvanyi, L. G. (2012). New insights on the role of CD8+CD57+ T-cells in cancer. OncoImmunology, 1(6), 954–956. https://doi.org/10.4161/onci.20307

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