Supramolecular hydrophobic guest transport system based on pillar[5]arene

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Abstract

A pillar[5]arene-based bioactive guest loading system has been developed, which can increase the solubility of the drug norharmane in aqueous medium, and also enable its pH-stimulated release. Furthermore, this supramolecular transport system reduces the toxicity of loaded guest.

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Qi, Z., Achazi, K., Haag, R., Dong, S., & Schalley, C. A. (2015). Supramolecular hydrophobic guest transport system based on pillar[5]arene. Chemical Communications, 51(51), 10326–10329. https://doi.org/10.1039/c5cc03955j

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