Spectrophotometric method for the determination of carboxin in its formulations and environmental samples

Abstract

Simple, precise, rapid, sensitive and accurate spectrophotometric methods have been developed for the estimation of carboxin in pure form and in its formulations. The first method is based on oxidative coupling of carboxin with 1,10-phenonthrolin in presence of ferric chloride to form orange colored product with λmax of 510 nm.The product obeyed Beer's law in the concentration range 1-10 mL (10 to 100 μg/mL) with molar absorptivity of 1.1425×103 Sandell's sensitivity 0.2061. The second method is based on the reaction of carboxin with 2,2'-bipyridine to form orange red colored product exhibiting λmax of 522 nm with molar absorptivity, Sandell's sensitivity 2.2605×103, 0.1041 respectively. It obeys Beer's law in the concentration range of 0.5-50 mL (5 to 50 μg/mL). The assay of results was found to be in good agreement with label claim. © Copyright E-Journal of Chemistry 2004-2011.