Electromechanical cell lysis using a portable audio device: Enabling challenging sample preparation at the point-of-care

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Abstract

Audio sources are ubiquitously available on portable electronic devices, including cell phones. Here we demonstrate lysis of Mycobacterium marinum and Staphylococcus epidermidis bacteria utilizing a portable audio device coupled with a simple and inexpensive electromagnetic coil. The resulting alternating magnetic field rotates a magnet in a tube with the sample and glass beads, lysing the cells and enabling sample preparation for these bacteria anywhere there is a cell phone, mp3 player, laptop, or other device with a headphone jack.

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Buser, J. R., Wollen, A., Heiniger, E. K., Byrnes, S. A., Kauffman, P. C., Ladd, P. D., & Yager, P. (2015). Electromechanical cell lysis using a portable audio device: Enabling challenging sample preparation at the point-of-care. Lab on a Chip, 15(9), 1994–1997. https://doi.org/10.1039/c5lc00080g

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