Immunoglobulin levels in methotrexate treated paediatric rheumatology patients

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Abstract

Retrospective review of serum immunoglobulin levels in 78 methotrexate treated paediatric rheumatology patients showed that IgG, IgA, and IgM levels fell significantly by 26%, 21%, and 17% respectively while on methotrexate. Six patients with systemic disease showed a fall in IgG to below the normal range.

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Rackham, O. J., Sills, J. A., & Davidson, J. E. (2002). Immunoglobulin levels in methotrexate treated paediatric rheumatology patients. Archives of Disease in Childhood, 87(2), 147–148. https://doi.org/10.1136/adc.87.2.147

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