Evaluation of an Epstein-Barr virus (EBV) immunoglobulin M enzyme- linked immunosorbent assay using a synthetic convergent peptide library, or mixotope, for diagnosis of primary EBV infection

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Abstract

An immunoglobulin M (IgM) enzyme-linked immunosorbent assay (ELISA) was developed by using a 24-amino-acid peptide of the 18-kDa Epstein-Barr virus (EBV) viral capsid antigen (VCAp18). IgM detection was increased by 23% by using this antigen. Detection of IgM antibodies to the EBV proteins in the new ELISA was 100% specific and 95% sensitive.

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APA

Tranchand-Bunel, D., Gras-Masse, H., Bourez, B., Dedecker, L., & Auriault, C. (1999). Evaluation of an Epstein-Barr virus (EBV) immunoglobulin M enzyme- linked immunosorbent assay using a synthetic convergent peptide library, or mixotope, for diagnosis of primary EBV infection. Journal of Clinical Microbiology, 37(7), 2366–2368. https://doi.org/10.1128/jcm.37.7.2366-2368.1999

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