Catalase-negative Staphylococcus aureus strain with point mutations in the katA gene

Abstract

Methicillin-susceptible catalase-negative Staphylococcus aureus strain UCN61 was isolated from an arterial leg ulcer. The deduced sequence of the structural katA gene for the catalase was 99% identical to those of other S. aureus strains. Two mutations were identified in katA from S. aureus UCN61, including one leading to a substitution of key histidine 58 by a tyrosine. Copyright © 2008, American Society for Microbiology. All Rights Reserved.