Therapeutic effect of Shengmai injection on respiratory function in chronic obstructive pulmonary disease

Abstract

OBJECTIVE: To explore the therapeutic effect of Shengmai injection (SMI) on respiratory function in chronic obstructive pulmonary disease (COPD). METHODS: Twenty patients with COPD were continuously treated with SMI by intravenous drip in 14 days and examined the lung vital capacity (VC), forced vital capacity (FVC), forced vital capacity of the first second (FEV1), FEV1/FVC, maximum voluntary ventilation (MVV), maximum inspiratory pressure (MIP), load respiratory time (LT), 6 minute walk distance (6 MWD), arterial blood gas analysis, and Brog dyspnea scale before and after treatment respectively and compared with itself or control group. RESULTS: After treatment all parameters of the treatment group were better than those of control group or itself before treatment except for FVC and FEV1/FVC. There were significant difference (P < 0.05). CONCLUSION: SMI can improve respiratory function in COPD. So it is an effective rehabilitative measure in treating COPD.