The efficacy of traditional formulation on quality of life and fatigue in multiple sclerosis patients: a randomized double-blind placebo-control clinical trial

Abstract

Objective: According to effects that cinnamon, ajwain and Iranian borago shows in involving mechanisms in MS and MS animal model, we decided to survey the affect of traditional formulation on MS patient by clinical trial. Methods: in a double blind randomized clinical trial study, 60 patients with (MS) observed. They take formulation 15cc per day, fill the MSQOL-54, and fatigue questionnaires every month. The data were analyzed with 18th version of SPSS, independent t-Test and repeated measure tests. The p-value for tests was 0.05. Results: the mean quality of life and fatigue of patient with MS were significantly changed during 3 month. Conclusion: most patients with MS had better quality of life during 3 month and get less tired. In some patient tremor and pain reduce. Because of good result and revenue of formulation, it seems to be useful for MS patient.