Unanticipated multiplex PCR-based identification of polymicrobial blood culture resulting in earlier isolation, determination of susceptibilities, and optimization of clinical care

Abstract

We describe a case of polymicrobial bloodstream infection with six organisms identified by multiplex PCR that was initially thought to be a monomicrobial infection. Early recognition of specific Gram-positive, Gram-negative, and fungal organisms and resistance elements allowed significantly more rapid optimization of therapy.