Regioselective remote C–H fluoroalkylselenolation of 8-aminoquinolines

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Abstract

Herein, the direct C-5 fluoroalkylselenolation of 8-aminoquinolines is described. The Pd-catalyzed reaction is performed with the in situ generated fluoroalkylselenyl chloride and various 8-aminoquinoline amides or sulfonamides. The desired products were formed in moderate to excellent yields.

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Ghiazza, C., Ndiaye, M., Hamdi, A., Tlili, A., & Billard, T. (2018). Regioselective remote C–H fluoroalkylselenolation of 8-aminoquinolines. Tetrahedron, 74(45), 6521–6526. https://doi.org/10.1016/j.tet.2018.09.048

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