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Solid-Phase Synthesis and Catalytic Screening of Polystyrene Supported Diphosphines

Topics in Catalysis (2016) 59(19-20) 1793-1799
DOI: 10.1007/s11244-016-0700-1
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Abstract

An efficient modular method towards the synthesis of a library of polystyrene supported diphosphine ligands by combining solid-phase synthesis with rational ligand design has been developed. These supported ligands, obtained in quantitative yield, were efficiently and effectively screened in Rh-catalysed asymmetric hydrogenation of several benchmark substrates.

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Samuels, M. C., Heutz, F. J. L., Grabulosa, A., & Kamer, P. C. J. (2016). Solid-Phase Synthesis and Catalytic Screening of Polystyrene Supported Diphosphines. Topics in Catalysis, 59(19–20), 1793–1799. https://doi.org/10.1007/s11244-016-0700-1

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