Efficacy of tramadol as analgesic and mixed with ketamine, xylazine as anesthetic in rabbits

Abstract

This study were performed to evaluate the efficacy of Tramadol as analgesic and efficacy of  using Tramadol in combination with other drugs like Ketamine and Xylazine in anesthetic protocols in rabbits.    15 adult New Zealand white rabbits divided to 3 equal groups were anesthetized intramuscularly in one syringe, group 1 with Tramadol 15 mg/kg B.W, group 2 with Tramadol 15mg/Kg B.W and Ketamine 30mg/Kg B.W, group 3 with Tramadol 15mg/Kg B.W and Ketamine 30mg/Kg B.W and Xylazine 5mg/Kg B.W, physiologic parameters were evaluated including : body temperature, heart rate, respiratory rate, muscle relaxation, analgesia and stages of anesthesia ( Induction of anesthesia, surgical anesthesia and recovery time).The most significant changes were reported in G3 (T15K30X5) and this combination is useful regimen clinically for anesthetize rabbits due to the fast of induction anesthesia and the long surgical duration of anesthesia.